Based on the the GeneMind GenoScout CNV library preparation reagent, this low-pass whole genome sequencing method enables fast and accurate analysis of abortion tissue and blood samples without the need for cell culture. It supports comprehensive evaluation of aneuploidies of the 23 pairs of chromosomes, as well as microdeletions and microduplications larger than 100 kb.
This solution covers the entire workflow from nucleic acid extraction to data analysis, which can greatly facilitate your research work.
Aneuploidy, large fragment deletion/duplication, and CNVs over 100 kb can be detected simultaneously in a single assay
Supports both manual and automated library preparation; seamless integration with the bioinformatics analysis platform
NIPT and CNV-seq can be sequenced in the same run
High detection accuracy with good data stability
| Parameter | CNV-seq | ||
| Sample volume | gDNA ≥ 10 ng | ||
| Sample type | Abortion tissue, Blood | ||
| Sequencing platform | FASTASeq™ 300 | GenoLab™ M | SURFSeq™ 5000 |
| Number of samples per run (1 Positive Control +1 Negative Control included) | 1 FCM: 4 | 1 FCM: 12 | 1 FCH: 96 |
| 1 FCH: 12 | 1 FCH: 24 | 1 FCP: 160 | |
| 1 FCP: 24 | / | / | |
| Turnaround time¹ | 22-27 h | 30.5-34.5 h | 31.5-35.5 h |
| Read length | SE75 for GenoLab™ M, FASTASeq™ 300; SE50 for SURFSeq™ 5000 | ||
| Average unique reads/sample | GenoLab™ M / FASTASeq™ 300 ≥ 15 M; SURFSeq™ 5000 ≥ 20 M | ||
| Report generation | Local analysis and report system | ||
1. Please note that the turn-around-time shown in the table is validated in GeneMind's lab, just for reference. It may bedifferent due to the local situation, such as the sample volumes, lab equipment and the proficiency of operator
