Noninvasive prenatal testing (NIPT) performed with the GenoLab™ M, FASTASeq™ 300, and SURFSeq™ 5000 sequencing platforms enables reliable screening results for fetal chromosomal aneuploidies as early as nine gestational weeks from a single 10 mL tube of maternal blood. Compatible with G tube, K tube, and Streck tube.
This solution covers the entire workflow from nucleic acid extraction to data analysis, which can greatly facilitate your research work.
The test achieves over 99% overall sensitivity based on a study of more than 100,000 pregnancies
From sample to report: simplified operation
Automated and localized data analysis with reports generated in 16.5 hours
Compatible with low-, medium-, and high-throughput sequencing platforms
Offering flexible options for both manual and automated workflows
The workflow supports the GeneScout EM Automated Nucleic Acid Extractor, MrLH-96 Automated Sample Preparation System, and the AIRS Automated Integrated Report Server
|
Product |
Trisomy 21，18，13 |
6 Sex Chromosome Aneuploidies |
19 autosomal Aneuploidies（SCAs） |
Microdeletion/duplications syndromes |
Sex identification, fetal fractionestimation |
|
NIPT basic |
√ |
—— |
—— |
—— |
√ |
|
NIPT Standard |
√ |
√ |
√ |
—— |
√ |
|
NIPT Plus |
√ |
√ |
√ |
60 |
√ |
|
NIPT Pro |
√ |
√ |
√ |
90 (Including DiGeorge Syndrome) |
√ |
| Parameter | NIPT Basic | NIPT Standard | NIPT Plus | NIPT Pro | |
| Sample Volume | 10 mL of a single tube of maternal blood | ||||
| Library preparation | PCR | ||||
| Method | Low-pass whole genome sequencing | ||||
|
Number of samples per run (1 Positive Control +1 Negative Control included) |
FASTASeq™ 300 | 1 FCM: 24 | 1 FCM: 16 | 1 FCM: 24 | / |
| 1 FCH: 48 | 1 FCH: 32 | 1 FCH: 48 | / | ||
| 1 FCP : 96 | 1 FCP: 64 | / | 1 FCP: 20 | ||
| GenoLab™ M | 1 FCM: 48 | 1 FCM: 32 | 1 FCM: 24 | / | |
| 1 FCH: 96 | 1 FCH: 64 | 1 FCH: 48 | 1 FCH: 20 | ||
| SURFSeq™ 5000 | 1 FCH: 250 | 1 FCH: 160 | 1 FCH: 96 | 1 FCH: 64 | |
| 1 FCP: 450 | 1 FCP: 300 | 1 FCP: 180 | 1 FCP: 120 | ||
| Read length | FASTASeq™ 300 and GenoLab™ M | SE75 | |||
| SURFSeq™ 5000 | SE50 | ||||
| Average Unique Reads / sample | FASTASeq™ 300 and GenoLab™ M | ≥3.5 M | ≥5 M | ≥7 M | ≥16 M |
| SURFSeq™ 5000 | ≥5 M | ≥7 M | ≥12 M | ≥20 M | |
| Turnaround time | FASTASeq™ 300 | 16.5-21.5 h | |||
| GenoLab™ M | 25-29 h | ||||
| SURFSeq™ 5000 | 16-30 h | ||||
| Report generation | Local analysis and report system | ||||
