GeneMind comprehensive pan-cancer solution uses the GenoScout Onco-580 gDNA Library Preparation Kit. It targets over 580 genes related to solid tumors based on hybrid capture technology, covering all major variant classes and gene signatures (TMB, MSI) that are related to targeted therapy, chemotherapy, immunotherapy, and hereditary tumor risk assessment. GeneMind's pan-cancer solution provides comprehensive medication guidance for patients.
Microsatellite instability (MSI) detection
Mismatch repair (MMR) related gene detection and tumor mutation burden (TMB) assessment
Covering targeted medication, chemotherapy, immunotherapy, and hereditary tumor risk assessment
Detecting homologous recombination repair (HRR)/DNA Damage Repair (DDR) - related mutations to guide the treatment of PARP inhibitors
Enabling simultaneous analysis of SNVs, InDels, CNVs, fusions and genomic signatures
Providing broad genomic information from a single hybrid capture assay
One test covers all major variant classes and gene signatures (TMB, MSI)
Featuring high sensitivity, this solution can detect SNVs and InDels with minimum detectable AF values of 1% for tissue and 0.2% for ctDNA
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Product |
Pan-Cancer 580 Panel |
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Methods |
Hybrid capture |
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Gene number |
580+ |
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Panel size |
2149 kb |
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Variants type |
SNVs, InDels, CNVs, SVs |
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Input quantity |
20 ng ~ 500 ng DNA |
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Sample types |
FFPE, fresh tissue, plasma, white blood cells, etc. |
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Mapping rate |
99% |
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On-target rate |
>70% |
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Coverage uniformity |
96% |
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Sequencing platform |
FASTASeq 300 |
GenoLab M |
SURFSeq 5000 |
FASTASeq S |
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No.of sample/FC |
Tissue (≥ 6 Gb) |
1 FCM: 4 1 FCH: 8 1 FCP：16 |
1 FCM: 8 1 FCH: 16 |
1 FCM: 24 1 FCH: 90 1 FCP：160 |
1 FCM: 1 |
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Plasma (≥50 Gb) |
1 FCH: 1 1 FCP：2 |
1 FCM: 1 1 FCH: 2 |
1 FCM: 2 1 FCH: 8 1 FCP：16 |
- |
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White blood cell(≥2Gb) |
1 FCM: 12 1 FCH: 28 1 FCP: 56 |
1 FCM: 28 1 FCH: 56 |
1 FCM: 56 1 FCH: 240 1 FCP: 432 |
1 FCL: 2 1 FCM：4 |
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Turn-around-time |
3-5 days |
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Report generation |
Local analysis and report system |
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