GenoLab M

The high-throughput sequencing system GenoLab M adopts the surface-restricted fluorescence sequencing technique (SURFseq) based on surface amplification to identify the optical signals of bases. Its sequencing-by-synthesis approach delivers fast speed, high flexibility, high accuracy, and low cost. GenoLab M can be configured to run 1 flow cell alone or 2 flow cells simultaneously---enabling a scalable solution tailored to your specific research needs. With single or dual flow cell options, the system can be tuned to meet output needs ranging from 37Gb to 300Gb per run, supporting a wide range of applications.

* For Research Use Only. Not intended for use in diagnostic or clinical procedures. Not available in all countries.

Highlights

Performance Parameters

Applications

Specification Parameters

Ordering Information

Documents

High Integration

Libraries can be directly used for sequencing after preparation

Multiple throughputs and read lengths available
High Accuracy

Combined with a high-sensitivity fluorescence signal detection system to maximize sequencing accuracy
High Compatibility

Compatible to mainstream NGS libraries and bioinformatics analysis software

Compatible with GeneMind bioinformatics analysis software
High Flexibility

Pre-mixed cartridges, integrating amplification and sequencing

Single/dual chips rolling on the machine

GenoLab M V4.0 Kit
Flow Cell	Lane	Throughput（Reads/FC）	Type	Read Length	Data output¹	Q30¹	TAT²(h)
FCM	4	250M	75cycles	SE75	18Gb	≥85%	13 hr
			150cycles	PE75	37.5Gb		22 hr
			300cycles	PE150	75Gb		38 hr
FCH	4	500M	75cycles	SE75	37.5Gb		15 hr
			150cycles	PE75	75Gb		28 hr
			300cycles	PE150	150Gb		50 hr

1. This parameter is obtained based on the average of multiple test resuts of GeneMind P3 standard library. The data output and the proportion of high-quality data are affected by factors such as sample type, sample quality and effective flow cell utilization. The actual performance may vary.

2. The TAT (tumaround time)fora standard run (paired-end 8+8 indexing)encompasses the entire process from library loading to the generationtion of base-called sequence files.

Applications	Read Length	Data/sample	Number of samples/FC
Applications	Read Length	Data/sample	FCH-250M	FCH-500M
Oncology Panel (30genes)-Tissue	PE150	6 Gb	48	96
Oncology Panel (30genes)-Plasma	PE150	50 Gb	8	16
NIPT Basic	SE75	5M reads	48	96
NIPT Standard	SE75	7M reads	32	64
NIPT Plus	SE75	10M reads	24	48
NIPT Pro	SE75	20M reads	/	20
TB-tNGS	SE100	2M reads	96	192
PGT-A	SE75	5M Reads	36	64
CNVseq	PE150	20M reads	12	24
HLA (11gene)	PE150	0.6 Gb	96	192

The above sample numbers for different applications are only for reference. User need to adjust the sample numbers according to the actual experiment.

Specification
Dimensions	1170mm(L)×690mm(W)×600mm(H)
Weight	200kg
Operating Environment	Temperature: 19℃-25℃
	Humidity: 20%-80% relative humidity, non-condensing
	Altitude: below 300m
Instrument Control Computer	Operating System: Windows 10
	CPU: IntelXeon Silver 4216 2.1GHz
	Memory: 32GB*6 DDR4
	Hard Drive1: 1TB SSD
	Hard Drive2: 10TB HDD

GenoLab M V4.0 Kit
Catalog Number	Product Name	Specification
SQ00010	GenoLab M Sequencing System Set	RUO
S000243	GenoLab M Sequencing Kit V4.0（FCM-D SE075-D）	FCM-D SE075-D
S000244	GenoLab M Sequencing Kit V4.0（FCM 150cycles）	FCM 150cycles
S000245	GenoLab M Sequencing Kit V4.0（FCM 300cycles）	FCM 300cycles
S000246	GenoLab M Sequencing Kit V4.0（FCH-D SE075-D）	FCH-D SE075-D
S000247	GenoLab M Sequencing Kit V4.0（FCH 150cycles）	FCH 150cycles
S000248	GenoLab M Sequencing Kit V4.0（FCH 300cycles）	FCH 300cycles

For Research Use Only. Not intended for use in diagnostic or clinical procedures. Not available in all countries.

GenoLab M brochure