Structural variations (SV) are critical genome changes affecting human diseases. Although many hybridization-based methods exist, evaluating SVs through next-generation sequencing (NGS) data is still necessary for broader research exploration. In

SARS-CoV-2 and influenza A viruses are similar in transmission and respiratory symptoms but differ in virulence, treatment and vaccine availability. Metagenomic nextgeneration sequencing (mNGS) does not depend on culture and

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is often absent or at low levels in the cerebrospinal fluid (CSF) of patients with previous SARS CoV-2-associated Guillain-Barre syndrome (GBS). This has

The Omicron BA.5.2 variant of SARS-CoV-2 has undergone several evolutionary adaptations, leading to multiple subvariants. Rapid and accurate characterization of these subvariants is essential for effective treatment, particularly in critically

To study the molecular mechanisms responsible for inducing the spatial proliferation of malignant melanomas (MM), three-dimension (3D) spheroids were produced from several MM cell lines , and their 3D architectures

In this study, we measured cytotoxicity by several anti-tumor agents, cellular metabolism including mitochondrial and glycolytic functions by a Seahorse bio-analyzer, the physical properties, size and stiffness of the 3D

Mycotoxins have a negative impact on aquaculture and agriculture, entering plant feed as a result of the processing of postharvest products obtained from fields infected with phytopathogenic fungi. In this

Tumor is a multicomponent system with complex in -tercellular interactions that play a central role in dis-ease progression and response to therapy. An essential requirement for single-cell RNA sequencing in

This study aimed to characterize the genomic epidemiology of human adenoviruses (HAdVs) in Hubei, China, using metagenomic next-generation sequencing (mNGS). In total, 25 HAdV-positive samples collected from 21 pediatric patients were

Ischemic heart disease resulting from I/R injury is associated with high morbidity. Identifying cell and molecular mechanisms that contribute to cardiomyocyte death after reperfusion will be critical for development of adjunctive