m6A is an RNA modification that is abundant in mammalian cells and catalyzed by the methyltransferase complex (MTC), of which the METTL3/METTL14 heterodimer is the catalytic subunit of MTC. Studies have

N6-methyadenosine (m6A) is a prevalent and dynamic modification on mRNAs and diverse types of noncoding RNAs. The landscape of N6-methyadenosine (m6A) on different RNA isoforms is still incompletely understood. Here, in HEK293T cells,

Hermansky–Pudlak syndrome (HPS) is a rare disease inherited in the autosomal recessive mode, including 11 clinical genetic subtypes. They are associated with impaired function of the BLOC protein complex (Biogenesis

Neuroendocrine neoplasms are a rare and heterogeneous group of neoplasms. Small-sized (≤2 cm) pancreatic neuroendocrine tumors (PanNETs) are of particular interest as they are often associated with aggressive behavior, with

Human adenoviruses (HAdVs) are common pathogens that cause respiratory infections and can also lead to various health issues such as cystitis, conjunctivitis, gastrointestinal diseases, and even encephalitis. Genomic research on

Genomic studies of urothelial carcinoma have identified inactivation of tumor suppressor genes (e.g., TP53, ARID1A) and activation of oncogenes (e.g., FGFR3, PIK3CA). 3′ RACE is a useful method for identifying