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Comparative analysis of clinicaland immunological profilesacross Omicron BA.5.2 subvariants using next generation sequencing in a Chinese cohort

The Omicron BA.5.2 variant of SARS-CoV-2 has undergone several evolutionary adaptations, leading to multiple subvariants. Rapid and accurate characterization of these subvariants is essential for effective treatment, particularly in critically ill patients. This study leverages GeneMind GenoLab M platform to elucidate the clinical and immunological features across different Omicron BA.5.2 subvariants.

This study reveals that critically ill patients infected with different Omicron BA.5.2 subvariants experience similar levels of cellular immune dysfunction and inflammatory response. Our findings underscore the utility of NGS in the comprehensive assessment of infectious diseases, contributing to more effective clinical decision-making.

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