A recent study published by BMC Genomics compared the relative performance of GenoLab M and Illumina NextSeq 2000 for 10x Genomics Visium spatial sequencing.
In order to assess concordance of the Illumina NextSeq 2000 and GenoLab M sequencing platforms for spatial transcriptomics, the study sequenced three 10x Genomics Visium libraries of FFPE ovarian tumor tissues. The research demonstrates that GenoLab M sequencing platform generates consistent with NextSeq 2000 sequencing results. Sequencing quality metrics indicated highly comparable base calling accuracy in UMI sequence, spatial barcode sequence, and probe read sequence. GenoLab M therefore has excellent performance in sequencing quality and is suitable for 10x Genomics Visium spatial transcriptomics.
