Last week, a collaborative study by the Hebei Agricultural University and the Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, was published in the top-tier journal Advanced Science (Impact Factor 14.1), entitled “Autopolyploidization-Induced Chromatin Remodeling Regulates Leaf Size Variation in Brassica rapa” . The team constructed materials of different ploidy levels (haploid, diploid, and tetraploid) and, by integrating multi-omics technologies including ATAC-seq, ChIP-seq, and RNA-seq, successfully revealed the dynamic chromatin landscape during two consecutive whole-genome duplications from haploid to tetraploid.
The researchers utilized the GeneMind SURFSeq 5000 platform to provide high-quality RNA-seq data for three independent haploid genotypes, three independent diploid genotypes, and one tetraploid genotype in this study, laying a solid foundation for subsequent in-depth analysis.